I’d probably go with Harper, Brown, Samir/Malik, Purifoy, and Anfernee.
I like putting Brown/Samir on Kyle Guy/Ty Jerome and Purifoy on Hunter. I just hope Jared can be aggressive without fouling. I like having AMac in to have 5 outside capable guys, but I also like having Wiley in to pull the pack line inside a few feet as @Brad_ATX explicitly mentioned. Although this results in two slightly different offenses depending on who is at the 5.
Ultimately, unless we are on a big run with a certain lineup, I would throw different lineups at them throughout the game. If depth is one of our advantages, we should use it to the fullest